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Friday, March 5th 2010
FDA OKs generic Flomax capsules
WASHINGTON - The U.S. Food and Drug Administration says it
has approved the first generic version of Flomax (tamsulosin)
capsules to treat benign prostatic hyperplasia. The FDA said
the condition occurs in older men when an enlarged prostate
gland causes urination problems. The most common symptoms
include a weak stream during urination, urgency, leaking or
dribbling, as well as more frequent urination, especially
at night. The National Institutes of Health said BPH rarely
causes symptoms before age 40, but more than half of men in
their 60s and as many as 90 percent of men older than 70
have such symptoms. "The approval of generic tamsulosin
offers greater access to a widely used treatment for BPH,"
said Gary Buehler, director of the FDA's Office of Generic
Drugs. "FDA is committed to making generic drugs available to
patients and these drugs meet the same rigid standards as the
brand name drugs." Generic tamsulosin capsules are manufac-
tured by IMPAX Laboratories Inc. of Haywood, Calif.
Scientist turns skin cells into heart cell
HOUSTON - A University of Houston scientist says he has de-
veloped a stem cell technique that might lead to new treat-
ments for Alzheimer's, diabetes and other diseases. Pro-
fessor Robert Schwartz, head of the university's Center for
Gene Regulation and Molecular Therapeutics, said he devised
a method that allows the reprogramming of ordinary human
skin cells into heart cells that are similar to embryonic
stem cells. Schwartz and his colleagues said the cells could
be implanted and grown into fully developed beating heart
cells, reversing the damage caused by previous heart attacks.
The new cells would replace the damaged cardiac tissue that
weakens the heart's ability to pump, develops into scar
tissue and causes arrhythmias. The researcher said early
clinical trials using reprogrammed cells on actual heart
patients could begin within one or two years. Schwartz said
he and his team are now working on turning induced stem
cells into skeletal muscle cells to treat muscular dystrophy.
"We're trying to advance science in ways folks never even
dreamed about," Schwartz said. "The idea of having your own
bag of stem cells that you can carry through life and use
for tissue regeneration is at the very cutting edge of sci-
ence."
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New therapy suggested for liver fibrosis
BARCELONA, Spain - Spanish medical scientists say they've
found that lab rats treated with ghrelin, a stomach hormone,
displayed a reduction in liver fibrosis. The scientists at
Barcelona Hospital said ghrelin reduced the amount of fibro-
genic cells by 25 percent in the treated rodents, as well as
preventing acute liver damage and reducing oxidative stress
and inflammation. Dr. Ramon Bataller, lead author of the
study, said there are no current anti-fibrotic therapies for
patients with liver disease, such as hepatitis, cirrhosis
and liver cancer. "Our aim was to determine if recombinant
ghrelin could regulate the formation of fibrous tissue assoc-
iated with chronic liver damage," Bataller said. "In our
study, we demonstrate that recombinant ghrelin regulates
the fibrogenic response of the liver to acute and chronic
disease." He said the study's results indicate ghrelin might
be useful in treating patients with liver disease and fibro-
sis by preventing scar tissue formation. "Further studies
should evaluate the safety and efficacy of ghrelin in pati-
ents with chronic liver disease," the researchers said.
The findings are reported in the journal Hepatology.
Celiac disease immune system defects ID'd
LONDON - British-led medical researchers say they have ident-
ified four aspects of immune system disturbances that lead
to the development of celiac disease. The findings led by
scientists at Barts and the London School of Medicine and
Dentistry -- the medical school of the Queen Mary University
of London -- brings to nearly 40 the different inherited risk
factors that predispose to the disease. Professor David van
Heel said the findings could speed the way towards improved
diagnostics and treatments for the autoimmune disease and
lead to insights into related conditions such as type 1 dia-
betes. "We can now shed light on some of the precise immune
disturbances leading to celiac disease," said van Heel, who
said the study also shows substantial evidence suggesting a
shared risk between the gene associated with celiac disease
and many other common chronic immune mediated diseases.
Celiac disease is an autoimmune disease triggered by intol-
erance to gluten that prevents normal absorption of nutri-
ents. If undetected it can lead to severe health problems
including anemia, poor bone health, fatigue and weight loss.
The study appears in the early online edition of the journal
Nature Genetics.
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Study focuses on nevirapine HIV therapy
BIRMINGHAM, Ala. - U.S. scientists say women given nevira-
pine to protect the fetus from HIV should not use that drug
for at least a year after childbirth. University of Alabama
at Birmingham researchers said despite nevirapine working
well to prevent mother-to-child transmission of the human
immunodeficiency virus, a single dose of nevirapine in in-
fected pregnant women can trigger resistance to some forms
of the AIDS-drug cocktail known as combination anti-retro-
viral treatment. Professor Jeffrey Stringer, who led the
study, said the nevirapine-induced resistance fades after
about 12 months. "This study shows that women who need treat-
ment more than 12 months after using nevirapine to prevent
mother-to-child transmission safely can use standard first-
line treatments in their countries," Stringer said. "Women
who need treatment sooner than that should use a combination
that does not contain nevirapine, typically (a) regimen that
contains protease-inhibitor drugs." The study that included
scientists from Zambia, Nairobi and Bangkok is reported in
the journal PLoS Medicine.
FDA: Nutritional knowledge is increasing
WASHINGTON - The U.S. Food and Drug Administration says more
than half of U.S. consumers say they often read food labels
when buying a product for the first time. That finding was
just released from the FDA's 2008 Health and Diet Survey,
which suggests nutritional knowledge is increasing. Among
other things, the survey showed:
-- More U.S. consumers know of the relationship between diet
and heart disease. Ninety-one percent knew of that link, up
8 percent from the 2002 survey.
-- Sixty-two percent of consumers know fats are a factor
related to heart disease, compared with 53 percent in 2002.
-- People's awareness that trans fats might raise the risk
of heart disease nearly doubled, from 32 percent in 2004 to
62 percent.
But the survey found differing degrees of trust about food
label claims, with 41 percent of consumers believing all or
most claims such as "low fat" or "high fiber" are accurate,
while 56 percent said some or none are true. The survey also
found 54 percent of people eat breakfast daily, while 8 per-
cent said they skip the meal. In contrast, 86 percent said
they eat dinner daily, while 1 percent said they always skip
it. The telephone survey of more than 2,500 U.S. adults --
the 10th such survey since 1982 -- had a margin of error of
2 percentage points. The report is available at
http://www.fda.gov/Food/ScienceResearch/ResearchAreas/ConsumerResearch/uc=
m193895.htm.
--------------- Health Tip Video of the Week ---------------
The Silent Male - The Fight Against Pain
Rating: 5
Did you know that women feel pain more acutely than men do?
In addition, women visit the doctor more often than men and
they do so earlier in their ailment. This actually may reduce
men's life expectancy.
http://www.evtv1.com/player.aspx?itemnum=14900
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