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Friday, January 8, 2009
Drug could slow ALS muscle weakening
BALTIMORE - A drug used to treat symptoms of epilepsy could
slow muscle weakening in patients with Lou Gehrig's disease,
scientists in Baltimore said. In a clinical trial on amyo-
trophic lateral sclerosis patients, the drug talampanel
showed the potential to slow the progression of the disease,
helping to preserve patients' ability to speak, walk and
dress themselves, researchers at Johns Hopkins University
said. The trial, involving 50 volunteers with ALS, showed
talampanel to be safe with limited, and tolerable, side
effects, Johns Hopkins neurologist Jeffrey Rothstein wrote
in a recent issue of the journal Amyotrophic Lateral Scler-
osis. Talampanel is a member of the benzodiazepine family,
which are anti-anxiety and muscle-relaxing agents that work
in the brain and spinal cord. The promise of talampanel is
especially important in ALS because only one other drug,
riluzole, exists to treat the fatal neurodegenerative dis-
ease. "Riluzole can extend life only modestly and hasn't
been shown to slow ALS symptoms so the need for better ther-
apy is real," Rothstein said.
Two-step nano cocktail targets tumors
SAN DIEGO - A cocktail of nano-sized particles introduced
into the bloodstream shows promise in adhering to and killing
cancerous tumors, scientists in San Diego say. Scientists at
the University of California-San Diego developed a system
containing two nano materials, each one-thousandth the dia-
meter of a human hair. One nano material of iron oxide was
designed to find and adhere to epithelial tumors in mice,
while a second nano material -- the anti-cancer drug doxo-
rubicin -- was fabricated to kill the tumors, biochemist
Michael Sailor said in a release Monday. "This study repre-
sents the first example of the benefits of employing a coop-
erative nano system to fight cancer," Michael Sailor said of
the results, which were to be published in an upcoming issue
of the Proceedings of the National Academy of Sciences.
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Coffee linked to less liver fibrosis
BETHESDA, Md. - Patients with chronic hepatitis C virus who
consumed about 2 1/4 cups of coffee with caffeine daily had
milder liver fibrosis, U.S. researchers found. Dr. Apurva
Modi, the lead author, and fellow researchers at the National
Institute of Diabetes and Digestive and Kidney Diseases de-
termined that for patients with chronic hepatitis C virus
other sources of caffeine beyond coffee did not have the same
therapeutic effect Liver fibrosis, or scarring of the liver,
is the second stage of liver disease, characterized by a
degradation of liver function due to accumulated connective
tissue. From January 2006 to November 2008, all patients
evaluated in the Liver Disease Branch of the National Insti-
tutes of Health were asked to complete a questionnaire to
determine caffeine consumption. Questions were asked per-
taining to: regular and diet soft drinks; regular and decaf-
feinated coffee; black, green, Chinese and herbal teas; cocoa
and hot chocolate; caffeine-fortified drinks; chocolate
candy; caffeine pills and medications with caffeine. The
study, published in the journal Hepatology, suggested that a
beneficial effect requires caffeine consumption above a
threshold of about 2 coffee-cup equivalents daily, but con-
sumption of soda, green or black tea containing caffeine was
not associated with reduced liver fibrosis.
A pat on the head may help remember meds
ST. LOUIS - U.S. and German researchers say patting one's
head after taking a medication may help a person remember
they've taken their daily medication. Study lead author
Mark McDaniel of Washington University in St. Louis says
doing something unusual -- such as taking their medication
while placing one hand on their head or in some other un-
usual or silly way, like crossing their arms -- can help
seniors remember whether they've already taken their daily
medications. This strategy may help prevent taking a danger-
ous second dose. "Our results indicate that older adults can
use these sorts of more complex motor tasks to effectively
reduce repetition errors in habitual prospective memory
tasks, such as taking a daily medication." McDaniel says in
a statement. The study examined the performance of older
adults averaging 72 years of years versus results from a
group of college students in the performance of cognitive
tasks using a keyboard. The findings were published in Aging,
Neuropsychology and Cognition.
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Study: Cellphone use fights Alzheimer's
TAMPA, Fla. - U.S. researchers say they're surprised to dis-
cover radiation from cellphones may protect against and even
reverse Alzheimer's disease. The researchers at the Florida
Alzheimer's Disease Research Center, led by University of
South Florida neuroscientist Gary Arendash, said exposing
old Alzheimer's mice to electromagnetic waves from cellphones
erased brain buildups of a harmful protein known as beta
amyloid and eliminated memory problems typical of Alzheimer's.
The radiation also prevented beta amyloid buildup in younger
Alzheimer's mice, the researchers said in a study funded in
part by the National Institute on Aging and published in the
Journal of Alzheimer's Disease. In fact, exposing normal
mice to cellphone radiation for two hours a day over seven
to nine months actually improved their cognitive abilities
compared with so-called control mice tested in a parallel
experiment for comparison, Arendash and colleagues said. The
highly controlled study let researchers isolate the effects
of cellphone exposure on memory from other lifestyle factors
such as diet and exercise, the researchers said. It involved
96 mice, most of which were genetically altered to develop
beta amyloid plaques and memory problems mimicking Alzheimer's
disease as they aged. "It surprised us to find that cellphone
exposure, begun in early adulthood, protects the memory of
mice otherwise destined to develop Alzheimer's symptoms,"
Arendash said. "It was even more astonishing that the electro-
magnetic waves generated by cellphones actually reversed mem-
ory impairment in old Alzheimer's mice."
Therapy aids cochlear implant of toddlers
HAIFA, Israel - An Israeli researcher says music therapy can
help toddlers with cochlear implants acquire speech. Dr. -
Dikla Kerem of the University of Haifa in Israel says music
gradually introduced can help toddlers bridge between the
quiet world before the implant and the world of sounds un-
folding following the operation. The study findings suggest
it is important parents and staff learn the best way to ex-
pose these children to music and how to use music for commun-
ication. Therapists should use an undirected approach, the
study says. "Music therapy is gradually penetrating the field
of rehabilitation, but there is still a lot of work to be
done in improving awareness of this important area," Kerem
says in a statement. The study was carried out in Israel as
a doctoral thesis for Aalborg University in Denmark. The
findings were presented at the "Brain, Therapy and Crafts"
conference held at the University of Haifa.
--------------- Health Tip Video of the Week ---------------
Health Tip: Foods That Lower LDL
Rating: 4.27
The perfect cholesterol-lowering recipe may be in your pantry!
http://www.evtv1.com/player.aspx?itemnum=11750
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