Diabetic Digest - Wednesday, June 27, 2012

Readers:

One of the enemies of the diabetic, especially in the summertime, is none other than dehydration.

The humidity is really getting to me. I've noticed that my water intake has increased quite a bit, but my urinary output is less frequent. What's going on?

In conditions such as this make sure that you are drinking
plenty of water. I know I've said this before, but it's important to remember. You don't often feel dehydrated until it's too late. Make sure you keep cool, drink fluids frequently and keep a close eye on your blood sugar.

Just a little reminder. I don't want to sound like a nag, I want you to enjoy the summer, just make sure that you are healthy and safe.

Regards,
Steve

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Questions? Comments? Email Steve

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*-- Diabetic News --*
Absolute Incretin Effect Reduced in Type 2 Diabetes
Both phases of insulin secretion impaired in T2DM; incretin primarily enhances first-phase secretion

MONDAY (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM) the absolute incretin effect is reduced compared with healthy individuals, but its relative importance is increased, particularly in first-phase insulin secretion, according to a study published online June 20 in Diabetes.

Hans Juergen Woerle, M.D., from Ludwig-Maximilians-University in Munich, Germany, and colleagues examined the role of incretins on insulin secretion in 12 healthy individuals and 12 patients with T2DM, using the hyperglycemic clamp technique.

The researchers found that, compared with patients with T2DM, intravenous glucose alone was associated with a significantly greater first- and second-phase insulin secretion in healthy individuals. In both groups, duodenal nutrition perfusion increased both phases of insulin secretion, with first-phase insulin secretion enhanced more in patients with T2DM (approximately eight- versus two-fold). Approximately 20 percent of the overall insulin secretion was attributable to glucose-related stimulation of insulin secretion. Infusion with the glucagon-like peptide 1 receptor antagonist exendin(9-39) reduced both phases of insulin secretion in both groups.

"In conclusion, both phases of insulin secretion are impaired in T2DM. In particular, the responsiveness to glucose in first-phase insulin secretion is blunted," the authors write. "The absolute incretin effect is reduced in T2DM; its relative importance, however, appears to be increased, highlighting its role as an important amplifier of first-phase insulin secretion in T2DM."

Original Article: Absolute Incretin Effect Reduced in Type 2 Diabetes

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*-- Diabetic Recipe --*
English Muffin Breakfast Pizza
Servings: 1
Prep time: 5 minutes
Cook time: 5 minutes
Total: 10 minutes

Ingredients
2 tablespoons reduced-fat cream cheese
1 teaspoon reduced-fat sour cream
1/2 English muffin
1 small ripe peach, peeled and sliced
ground cinnamon to taste
1/2 teaspoon light brown sugar

Directions
1. Preheat broiler.
2. In a small bowl, combine cream cheese and sour cream.
3. Spread evenly over English muffin half.
4. Arrange peach slices on top.
5. Sprinkle with some cinnamon and the brown sugar.
6. Broil until cheese browns around the edges (about 2 minutes).
7. Cut in half or quarters and eat warm.

Nutrition Information
Per serving: 185 calories (33% calories from fat), 6 g protein, 7 g fat (4.3 g saturated fat), 25 g carbohydrates, 3 g fiber, 22 mg cholesterol, 258 mg sodium
Diabetic exchanges: 1 1/2 carbohydrate (1 bread/starch, 1/2 fruit), 1 fat

Original Recipe: English Muffin Breakfast Pizza

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