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Diabetic Digest - Wednesday, February 10, 2010
Readers:
It's been snowing for more than twenty-four hours here
on the Southside of Chicago and that means one important
thing to my health... I just got a great deal of exercise.
I've been shoveling and shoveling and shoveling. I'm
really tired, but it's a good kind of tired. I'm sure that
I'll sleep very well tonight and have to shovel even more
tomorrow, which couldn't be better for my health and my
driveway. That seems to be where I get the majority of my
exercise during the winter months, but I know my limit-
ations. If it gets too intense out there then I'll just
borrow my neighbor's snowblower.
Take care of yourself, readers.
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Happy Valentine's Day!
Regards,
Steve
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Enzyme may hold key to reversing diabetes
NORFOLK, Va. - Scientists at Eastern Virginia Medical
School say targeting an enzyme known as 12-LO may be the
key to reversing Type 1 diabetes. "We've now confirmed
that 12-LO is a relevant target in humans, particularly
in the pancreas, and will help lead to new therapies,"
said Dr. Kaiwen Ma, a researcher in the school's Strelitz
Diabetes Center.
Twelve-Lo, or 12-lipoxygenase, is a protein-based enzyme
found in insulin-producing beta cells. When beta cells
die, the body no longer produces enough insulin to
regulate blood-sugar levels.
Twelve-Lo, in studies in mice and human tissue cultures,
has been shown to inflame beta cells and lead to their
death, Ma and his associates said in the February Journal
of Clinical Endocrinology.
Ma and his associates are teaming with researchers at the
National Institutes of Health to develop a drug that
targets 12-LO, halts damage to human insulin-producing
cells and encourages cell regeneration, the school said
in a release.
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Wireless glucose monitors on horizon
CAMBRIDGE, England - An algorithm that analyzes glucose
levels could lead to wireless devices that recommend
insulin adjustments in type 1 diabetics, British scientists
said.
In a study on children, researchers at the University of
Cambridge found an algorithm that analyzed glucose levels
and suggested adjustments in insulin doses was more effect-
ive than standard diabetes management devices, The New
York Times reported Friday.
The discovery someday could aid millions of parents world-
wide who need to monitor their children's insulin levels
several times nightly to ensure blood sugar levels are
stable, the researchers said in Friday's issue of The
Lancet, a British medical journal.
The algorithm could be incorporated into a new generation
of wireless devices that act as an "artificial pancreas,"
mimicking the way a healthy pancreas works by sensing
unstable glucose levels and dispensing insulin in the
correct dose at the correct time.
Today's standard system involves a glucose monitor that
operates separately from a preprogrammed insulin pump.
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Diabetic Recipe
Raspberry Thumbprints
(makes 16 cookies)
1/4 cup (60 g) margarine, softened
3 tablespoons (36 g) sugar
1 large egg white
1 teaspoon (5 ml0 vanilla extract
1 1/2 cups (200 g) sifted cake flour
refrigerated butter-flavored cooking spray
3 tablespoons (60 g) no sugar added raspberry fruit spread
1. In a large bowl, cream margarine and sugar until light
and fluffy. Add egg white and vanilla. Beat well. Stir in
flour.
2. Using your hands, form dough into a ball. Wrap in
plastic wrap and chill for at least 30 minutes.
3. Preheat oven to 350°F (180°C), Gas Mark 4. Shape dough
into 1-inch (2.5 cm) balls. Place 2 inches (5 cm) apart
on a cookie sheet which has been lightly coated with
cooking spray.
4. Using your thumb, press a hole in the center of each
cookie. Bake for 8 to 10 minutes, until golden. Cool
completely on wire racks.
5. Spoon 1/2 teaspoon (2.5 ml) of the raspberry fruit
spread into center of each cookie.
Per 1-cookie serving: 85 calories (31% calories from fat),
1 g protein, 3 g fat, trace dietary
fiber, 0 cholesterol, 43 mg sodium
Diabetic exchanges: 1 carbohydrate (bread/starch)
Copyright 1997-2010 Diabetic-Lifestyle.
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